Aminoguanidine hydrochloride

Modify Date: 2024-01-02 11:07:51

Aminoguanidine hydrochloride Structure
Aminoguanidine hydrochloride structure
Common Name Aminoguanidine hydrochloride
CAS Number 1937-19-5 Molecular Weight 110.546
Density N/A Boiling Point 261.4ºC at 760 mmHg
Molecular Formula CH7ClN4 Melting Point 162-166 °C(lit.)
MSDS Chinese USA Flash Point 111.9ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Aminoguanidine hydrochloride


Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy.

 Names

Name Aminoguanidine hydrochloride
Synonym More Synonyms

 Aminoguanidine hydrochloride Biological Activity

Description Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy.
Related Catalog

 Chemical & Physical Properties

Boiling Point 261.4ºC at 760 mmHg
Melting Point 162-166 °C(lit.)
Molecular Formula CH7ClN4
Molecular Weight 110.546
Flash Point 111.9ºC
Exact Mass 110.035927
PSA 87.92000
LogP 1.03640
Vapour Pressure 0.0116mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ME8430000
CHEMICAL NAME :
Guanidine, amino-, hydrochloride
CAS REGISTRY NUMBER :
1937-19-5
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C-H6-N4.Cl-H
MOLECULAR WEIGHT :
110.57
WISWESSER LINE NOTATION :
ZMYZUM &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2984 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,251,1926

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ME8430000
HS Code 2928000090

 Synthetic Route

~%

Aminoguanidine hydrochloride Structure

Aminoguanidine ...

CAS#:1937-19-5

Literature: Journal of Medicinal Chemistry, , vol. 49, # 26 p. 7897 - 7901

~%

Aminoguanidine hydrochloride Structure

Aminoguanidine ...

CAS#:1937-19-5

Literature: Gazzetta Chimica Italiana, , vol. 24 I, p. 453

~%

Aminoguanidine hydrochloride Structure

Aminoguanidine ...

CAS#:1937-19-5

Literature: Russian Journal of Applied Chemistry, , vol. 84, # 3 p. 400 - 406

~%

Aminoguanidine hydrochloride Structure

Aminoguanidine ...

CAS#:1937-19-5

Literature: Chemische Berichte, , vol. 44, p. 2713 Gazzetta Chimica Italiana, , vol. 24 I, p. 453

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles45

More Articles
AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

J. Pathol. 235(4) , 581-92, (2015)

Biomechanical strain imposed by age-related thickening of the basal lamina and augmented tissue stiffness in the prostate gland coincides with increased cancer risk. Here we hypothesized that the stru...

Structure elucidation of secondary metabolites isolated from the leaves of Ixora undulate and their inhibitory activity toward advanced glycation end-products formation.

Phytochemistry 108 , 189-95, (2014)

Three aromatic glycosides (1-3), two sulfur and nitrogen-containing compound glucosides (4, 5), and one flavonoid glycoside (6) were isolated from the leaves of Ixora undulata. Their structures were e...

Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.

Food Chem. Toxicol. 69 , 55-62, (2014)

Vicenin 2, isolated from a traditionally used medicinal plant Artemisia capillaris, is a 6,8-di-C-glucoside of apigenin which has been previously reported to possess a wide variety of pharmacological ...

 Synonyms

Aminoguanidine hydrochloride
AMINOGUANIDINE SALT
MFCD00039074
N1-aminoguanidine hydrochloride
Guanylhydrazine hydrochloride
aminoguanidinium chloride
Aminoguanidine hydrochoride
1-aminoguanidine hydrochloride
6-Hydroxydopamine hydrobromide
EINECS 217-707-7
D015 AMinoguanidine hydrochloride
GUANYLHYDRAZINEHCL
Aminoguanidine HCL
amino-guanidinhydrochloride
aminoguanidine monohydrochloride
Hydrazinecarboximidamide, hydrochloride (1:1)
Hydrazinecarboximidamide hydrochloride (1:1)
carbazamidine monohydrochloride
Aminoguanidine salts
GUANIDINE,AMINO-,MONOHYDROCHLORIDE
hydrazinecarboximidamide hydrochloride
Aminoguanidine (hydrochloride)
Top Suppliers:I want be here






Get all suppliers and price by the below link:

Aminoguanidine hydrochloride suppliers


Price: ¥78/10g

Reference only. check more Aminoguanidine hydrochloride price