Tubulysin
Modify Date: 2024-01-07 22:13:50
Tubulysin structure
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Common Name | Tubulysin | ||
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| CAS Number | 1943604-24-7 | Molecular Weight | 842.10 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H67N5O9S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TubulysinTubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system[1]. |
| Name | Tubulysin |
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| Description | Tubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system[1]. |
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| References |
| Molecular Formula | C44H67N5O9S |
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| Molecular Weight | 842.10 |