BOP

Modify Date: 2024-01-09 11:35:08

BOP structure	Common Name	BOP
	CAS Number	1947348-42-6	Molecular Weight	537.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₈N₃NaO₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BOP

BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins[1][2].

Name	BOP sodium

Description	BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Cytoskeleton >> Integrin
Target	α4β1 α9β1
References	[1]. R Blake Pepinsky, et al. Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1. Biochemistry. 2002 Jun 4;41(22):7125-41. [2]. Benjamin Cao, et al. Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat Commun. 2016 Mar 15;7:11007.

Molecular Formula	C₂₅H₂₈N₃NaO₇S
Molecular Weight	537.56
Storage condition	-20°C

DC Chemicals Limited
China
Product Name: BOP sodium
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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