(Fmoc-amino)-PEG12-C2-Carboxylic Acid

Modify Date: 2024-01-04 14:43:11

(Fmoc-amino)-PEG12-C2-Carboxylic Acid structure	Common Name	(Fmoc-amino)-PEG12-C2-Carboxylic Acid
	CAS Number	1952360-91-6	Molecular Weight	839.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₆₅NO₁₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Fmoc-amino)-PEG12-C2-Carboxylic Acid

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fmoc-NH-PEG12-CH2CH2COOH

Description	Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₂H₆₅NO₁₆
Molecular Weight	839.96
Storage condition	-20°C