Megazol
Modify Date: 2024-01-10 02:16:53
Megazol structure
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Common Name | Megazol | ||
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| CAS Number | 19622-55-0 | Molecular Weight | 226.21600 | |
| Density | 2g/cm3 | Boiling Point | 532.6ºC at 760 mmHg | |
| Molecular Formula | C6H6N6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 275.9ºC | |
Use of MegazolMegazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections[1]. |
| Name | 5-(1-methyl-5-nitroimidazol-2-yl)-1,3,4-thiadiazol-2-amine |
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| Synonym | More Synonyms |
| Description | Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections[1]. |
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| Related Catalog | |
| Target |
EC50: 0.01 μg/mL (T. b. brueei)[1] |
| In Vitro | Megazol has effective inhibitory against T. b. brueei AnTat 1-9 with an EC50 of 0.01 μg/mL[1]. |
| In Vivo | Megazol (i.p. or p.o.; 20, 80 mg/kg) shows cure the acute disease in T. b. brueei infected Swiss mice[1]. Megazol alone not causes cure of mice carrying a subacute infection with involvement of the central nervous system (CNS) [1]. Megazol have remission effect combined suramin, without further relapse from the CNS[1]. Animal Model: Swiss mice[1] Dosage: 20, 80 mg/kg Administration: i.p., p.o. Result: Cured infection at 20 mg/kg (i.p) and at 80 mg/kg (p.o). |
| Density | 2g/cm3 |
|---|---|
| Boiling Point | 532.6ºC at 760 mmHg |
| Molecular Formula | C6H6N6O2S |
| Molecular Weight | 226.21600 |
| Flash Point | 275.9ºC |
| Exact Mass | 226.02700 |
| PSA | 143.68000 |
| LogP | 1.53340 |
| Vapour Pressure | 2.01E-11mmHg at 25°C |
| Index of Refraction | 1.921 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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| megazol |
| Nitroimidazole thiadiazole |