GAP 26 trifluoroacetate salt structure
|
Common Name | GAP 26 trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 197250-15-0 | Molecular Weight | 1550.78 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C70H106N19O19S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GAP 26 trifluoroacetate saltGap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. |
| Name | Gap 26 |
|---|---|
| Synonym | More Synonyms |
| Description | Gap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. |
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| Related Catalog | |
| Target |
Gap Junction Protein[1] |
| In Vitro | Gap 26 is corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. Gap 26 (100-300 μM) dose-dependently reduces the rhythmic responses of rabbit superior mesenteric arteries, with IC50 of 28.4 ± 3.4 μM[1]. Gap 26 abolishes the inositol-1,4,5-trisphosphate (InsP3)-triggered ATP response and reduces the ATP release, but has no effect on gap junctional coupling[2]. |
| References |
| Molecular Formula | C70H106N19O19S |
|---|---|
| Molecular Weight | 1550.78 |
| PSA | 657.12000 |
| LogP | 1.84770 |
| Storage condition | 2-8℃ |
| Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg |
| M.W. 1550.78 C70H107N19O19S |
| VCYDKSFPISHVR |