Teduglutide

Modify Date: 2024-01-12 12:52:01

Teduglutide Structure
Teduglutide structure
Common Name Teduglutide
CAS Number 197922-42-2 Molecular Weight 3752.08000
Density N/A Boiling Point N/A
Molecular Formula C164H252N44O55S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Teduglutide


Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel syndrome (SBS) and Crohn's disease (CD)[1][2].

 Names

Name Teduglutide
Synonym More Synonyms

 Teduglutide Biological Activity

Description Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel syndrome (SBS) and Crohn's disease (CD)[1][2].
Related Catalog
References

[1]. Jeppesen PB, et al. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut. 2005 Sep;54(9):1224-31.

[2]. Buchman AL, et al; Teduglutide Study Group. Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease. Inflamm Bowel Dis. 2010 Jun;16(6):962-73.

 Chemical & Physical Properties

Molecular Formula C164H252N44O55S
Molecular Weight 3752.08000
Exact Mass 3749.80000
PSA 1649.52000
LogP 1.01630
Storage condition -20℃

 Synonyms

Revestive
ALX 0600
H-His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH
teduglutide
Gattex
Glucagon-like peptide II [2-glycine] (human)
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