Fmoc-L-propargylglycine

Modify Date: 2024-01-02 10:47:31

Fmoc-L-propargylglycine Structure
Fmoc-L-propargylglycine structure
 Common Name Fmoc-L-propargylglycine
CAS Number 198561-07-8 Molecular Weight 335.353
Density 1.3±0.1 g/cm3 Boiling Point 576.7±50.0 °C at 760 mmHg
Molecular Formula C20H17NO4 Melting Point 175ºC
MSDS Chinese USA Flash Point 302.6±30.1 °C

 Use of Fmoc-L-propargylglycine


Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative[1].

 Names

Name Fmoc-L-propargylglycine
Synonym More Synonyms

 Fmoc-L-propargylglycine Biological Activity

Description Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 576.7±50.0 °C at 760 mmHg
Melting Point 175ºC
Molecular Formula C20H17NO4
Molecular Weight 335.353
Flash Point 302.6±30.1 °C
Exact Mass 335.115753
PSA 75.63000
LogP 4.19
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.619
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant;
Safety Phrases S24-S25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

(2S)-2-Amino-4-pentynoic acid structure

(2S)-2-Amino-4-...

CAS#:23235-01-0

9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate structure

9H-fluoren-9-yl...

CAS#:102774-86-7

~66%

Fmoc-L-propargylglycine Structure

Fmoc-L-propargy...

CAS#:198561-07-8

Literature: Byrne, Cillian; McEwan, Paul A.; Emsley, Jonas; Fischer, Peter M.; Chan, Weng C. Chemical Communications, 2011 , vol. 47, # 9 p. 2589 - 2591
(2S)-tert-butyl 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-ynoate structure

(2S)-tert-butyl...

CAS#:857335-00-3

~96%

Fmoc-L-propargylglycine Structure

Fmoc-L-propargy...

CAS#:198561-07-8

Literature: Itoh, Hiroaki; Matsuoka, Shigeru; Kreir, Mohamed; Inoue, Masayuki Journal of the American Chemical Society, 2012 , vol. 134, # 34 p. 14011 - 14018
(2S)-2-Amino-4-pentynoic acid structure

(2S)-2-Amino-4-...

CAS#:23235-01-0

Fmoc-Osu structure

Fmoc-Osu

CAS#:82911-69-1

~61%

Fmoc-L-propargylglycine Structure

Fmoc-L-propargy...

CAS#:198561-07-8

Literature: Sminia, Tjerk Jacco; Pedersen, Daniel Sejer Synlett, 2012 , vol. 23, # 18 p. 2643 - 2646,4 Title/Abstract Full Text Show Details Sminia, Tjerk Jacco; Pedersen, Daniel Sejer Synlett, 2012 , vol. 23, # 18 p. 2643 - 2646
TETRAMETHYLBIPHOSPHINE structure

TETRAMETHYLBIPH...

CAS#:71460-15-6

~%

Fmoc-L-propargylglycine Structure

Fmoc-L-propargy...

CAS#:198561-07-8

Literature: Journal of the American Chemical Society, , vol. 134, # 34 p. 14011 - 14018
(S)-2-(benzhydrylidene-amino)-pent-4-ynoic acid tert-butyl ester structure

(S)-2-(benzhydr...

CAS#:326667-54-3

~%

Fmoc-L-propargylglycine Structure

Fmoc-L-propargy...

CAS#:198561-07-8

Literature: Journal of the American Chemical Society, , vol. 134, # 34 p. 14011 - 14018

 Synonyms

Fmoc-propargyl-Gly-OH
(S)-2-(Fmoc-amino)-4-pentynoic Acid
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-pentynoic acid
MFCD01075095
4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine
Fmoc-Pra-OH
(S)-N-Fmoc-2-(2'-propynyl)glycine
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