NNC 26-9100
Modify Date: 2025-09-14 16:20:57
NNC 26-9100 structure
|
Common Name | NNC 26-9100 | ||
|---|---|---|---|---|
| CAS Number | 199522-35-5 | Molecular Weight | 556.35 | |
| Density | 1.482g/cm3 | Boiling Point | 731.167ºC at 760 mmHg | |
| Molecular Formula | C22H25BrCl2N6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 395.996ºC | |
Use of NNC 26-9100NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2]. |
| Name | NNC 26-9100,1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea |
|---|---|
| Synonym | More Synonyms |
| Description | NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.482g/cm3 |
|---|---|
| Boiling Point | 731.167ºC at 760 mmHg |
| Molecular Formula | C22H25BrCl2N6S |
| Molecular Weight | 556.35 |
| Flash Point | 395.996ºC |
| Exact Mass | 554.04200 |
| PSA | 100.96000 |
| LogP | 6.14940 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.668 |
| InChIKey | UREJDUPKGMFJRU-UHFFFAOYSA-N |
| SMILES | S=C(NCCCc1cnc[nH]1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 |
|
Name: Thermal Shift Assay. Domain: start/stop: S229-K512
Source: ChEMBL
Target: Tyrosine-protein kinase ABL1
External Id: CHEMBL5060751
|
|
Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
|
|
Name: Thermal Shift Assay. Domain: start/stop: M1-K294
Source: ChEMBL
Target: Casein kinase I isoform delta
External Id: CHEMBL5063818
|
|
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
|
|
Name: Incucyte cell viability with HEK293T
Source: ChEMBL
Target: HEK-293T
External Id: CHEMBL5058565
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
|
|
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
|
|
Name: PDSP Secondary Binding target: ADRA2B - Compounds are tested at 10 uM concentration, ...
Source: ChEMBL
Target: Alpha-2B adrenergic receptor
External Id: CHEMBL5442195
|
|
Name: Thermal Shift Assay. Domain: start/stop: G861-E979
Source: ChEMBL
Target: Transcription intermediary factor 1-alpha
External Id: CHEMBL5068463
|
Total 252, Current Page 1 of 26
1
2
3
4
5
| Pam3CSK4 Biotin |