NNC 26-9100

Modify Date: 2024-01-02 14:47:24

NNC 26-9100 structure	Common Name	NNC 26-9100
	CAS Number	199522-35-5	Molecular Weight	556.35
	Density	1.482g/cm3	Boiling Point	731.167ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₅BrCl₂N₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	395.996ºC

Use of NNC 26-9100

NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2].

Name	NNC 26-9100,1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea
Synonym	More Synonyms

Description	NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Neurological Disease
References	[1]. Michael Ankersen, et al. Discovery of a Novel Non-Peptide Somatostatin Agonist with SST4 Selectivity. J. Am. Chem. Soc. 1998, 120, 7, 1368-1373. [2]. Sandoval KE, et al. Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism. Brain Res. 2013 Jul 3;1520:145-56.

Description

NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor

Research Areas >> Neurological Disease

References

[1]. Michael Ankersen, et al. Discovery of a Novel Non-Peptide Somatostatin Agonist with SST4 Selectivity. J. Am. Chem. Soc. 1998, 120, 7, 1368-1373.

[2]. Sandoval KE, et al. Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism. Brain Res. 2013 Jul 3;1520:145-56.

Density	1.482g/cm3
Boiling Point	731.167ºC at 760 mmHg
Molecular Formula	C₂₂H₂₅BrCl₂N₆S
Molecular Weight	556.35
Flash Point	395.996ºC
Exact Mass	554.04200
PSA	100.96000
LogP	6.14940
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.668

Pam3CSK4 Biotin

DC Chemicals Limited
China
Product Name: NNC269100
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

NNC 26-9100 suppliers

NNC 26-9100 price

NNC 26-9100

Use of NNC 26-9100

Names

NNC 26-9100 Biological Activity

Chemical & Physical Properties

Synonyms