Mal-Ala-Ala-PAB-PNP

Modify Date: 2025-08-27 09:33:46

Mal-Ala-Ala-PAB-PNP Structure
Mal-Ala-Ala-PAB-PNP structure
Common Name Mal-Ala-Ala-PAB-PNP
CAS Number 2003260-14-6 Molecular Weight 623.61
Density N/A Boiling Point N/A
Molecular Formula C30H33N5O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-Ala-Ala-PAB-PNP


Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Mal-Ala-Ala-PAB-PNP

 Mal-Ala-Ala-PAB-PNP Biological Activity

Description Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C30H33N5O10
Molecular Weight 623.61
InChIKey GEMSBDIHVHIIDT-PMACEKPBSA-N
SMILES CC(NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(C)C(=O)Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1
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