Fmoc-Ala-Ala-PAB

Modify Date: 2025-08-24 22:13:48

Fmoc-Ala-Ala-PAB Structure
Fmoc-Ala-Ala-PAB structure
Common Name Fmoc-Ala-Ala-PAB
CAS Number 1384263-83-5 Molecular Weight 487.55
Density N/A Boiling Point N/A
Molecular Formula C28H29N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-Ala-Ala-PAB


Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Fmoc-Ala-Ala-PAB

 Fmoc-Ala-Ala-PAB Biological Activity

Description Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADC 由一种抗体和 ADC 毒素分子通过 ADC 连接子组合而成[1]。
References

[1]. Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26(11):2261-78.  

 Chemical & Physical Properties

Molecular Formula C28H29N3O5
Molecular Weight 487.55
InChIKey WFJHIWKUWIKWLW-ROUUACIJSA-N
SMILES CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC(C)C(=O)Nc1ccc(CO)cc1
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