4-Phenyl-1,3-thiazol-2-amine

Modify Date: 2025-08-25 17:24:15

4-Phenyl-1,3-thiazol-2-amine Structure
4-Phenyl-1,3-thiazol-2-amine structure
Common Name 4-Phenyl-1,3-thiazol-2-amine
CAS Number 2010-06-2 Molecular Weight 176.238
Density 1.3±0.1 g/cm3 Boiling Point 363.4±11.0 °C at 760 mmHg
Molecular Formula C9H8N2S Melting Point 149-153 °C(lit.)
MSDS Chinese USA Flash Point 173.6±19.3 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name 4-phenyl-1,3-thiazol-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 363.4±11.0 °C at 760 mmHg
Melting Point 149-153 °C(lit.)
Molecular Formula C9H8N2S
Molecular Weight 176.238
Flash Point 173.6±19.3 °C
Exact Mass 176.040817
PSA 67.15000
LogP 2.14
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.660
InChIKey PYSJLPAOBIGQPK-UHFFFAOYSA-N
SMILES Nc1nc(-c2ccccc2)cs1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ2878000
CHEMICAL NAME :
Thiazole, 2-amino-4-phenyl-
CAS REGISTRY NUMBER :
2010-06-2
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H8-N2-S
MOLECULAR WEIGHT :
176.25
WISWESSER LINE NOTATION :
T5N CSJ BZ ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0001727
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00815

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H315-H318-H335
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R22
Safety Phrases S26-S36/37/39
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
RTECS XJ2878000
HS Code 2934100090

 Synthetic Route

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles1

More Articles
Pharmacological analysis of the mechanism of action of phenthiazamine, a piscine anesthetic.

J. Pharmacobiodyn. 3(2) , 85-93, (1980)

Phenthiazamine was developed by Sekizawa et al. as a centrally acting anesthetic for fish. Frog sympathetic ganglion was used as a model to elucidate the mechanism of its anesthetic action. The positi...

 4-Phenyl-1,3-thiazol-2-amineBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Binding affinity to oxidoreductase 1 (unknown origin) at 200 uM by surface plasmon re...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3414328
Name: Binding affinity to Plasmodium falciparum AMA1 at 200 uM by surface plasmon resonance...
Source: ChEMBL
Target: Apical membrane antigen 1
External Id: CHEMBL3414329
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Binding affinity to oxidoreductase 2 (unknown origin) at 200 uM by surface plasmon re...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3414327
Name: Binding affinity to protein kinase (unknown origin) at 200 uM by surface plasmon reso...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3414332
Name: Binding affinity to oxidoreductase 1 (unknown origin) by STD-NMR analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL3414333
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 Synonyms

MFCD00039680
2-Thiazolamine,4-phenyl
4-phenyl-2-aminothiazole
2-Amino-4-phenyl-1,3-thiazole
4-Phenyl-1,3-thiazol-2-amine
2-amino-4-phenylthiazol
4-Phenyl-2-thiazolylamine
Phenthiazamine
4-Phenylthiazol-2-amine
2-Amino-4-phenylthiazole
4-Phenyl-2-thiazolamine
4-phenyl-1,3-thiazole-2-amine
EINECS 217-926-8
4-Phenyl-thiazol-2-ylamine
Thiazole,2-amino-4-phenyl
T5N CSJ BZ ER
4-phenyl-1,3-thiazol-2-ylamine
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