4-Thiouridine 5′-triphosphate tetralithium

Modify Date: 2024-03-30 18:11:10

4-Thiouridine 5′-triphosphate tetralithium structure	Common Name	4-Thiouridine 5′-triphosphate tetralithium
	CAS Number	20188-72-1	Molecular Weight	523.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₁Li₄N₂O₁₄P₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-Thiouridine 5′-triphosphate tetralithium

4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in the study of crosslinking experiments, labeling of transcriptional complex[1][2].

Name	4-Thiouridine 5′-triphosphate tetralithium

Description	4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in the study of crosslinking experiments, labeling of transcriptional complex[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> P2Y Receptor Research Areas >> Inflammation/Immunology
Target	P2Y2 Receptor:35 nM (EC50) P2Y4 Receptor:350 nM (EC50)
References	[1]. Jacobson KA, et, al. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochem Pharmacol. 2006 Feb 14;71(4):540-9. [2]. Bartholomew B, et, al. RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes. J Biol Chem. 1986 Oct 25;261(30):14226-31.

Molecular Formula	C₉H₁₁Li₄N₂O₁₄P₃S
Molecular Weight	523.94

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4-Thiouridine 5′-triphosphate tetralithium

Use of 4-Thiouridine 5′-triphosphate tetralithium

Names

Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.