Glycine-2-13C

Modify Date: 2024-01-10 21:03:58

Glycine-2-13C Structure
Glycine-2-13C structure
Common Name Glycine-2-13C
CAS Number 20220-62-6 Molecular Weight 76.059
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C13CH5NO2 Melting Point 240ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

 Use of Glycine-2-13C


Glycine-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

 Names

Name 2-aminoacetic acid
Synonym More Synonyms

 Glycine-2-13C Biological Activity

Description Glycine-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 240ºC (dec.)(lit.)
Molecular Formula C13CH5NO2
Molecular Weight 76.059
Exact Mass 76.035385
PSA 63.32000
Index of Refraction 1.461
Storage condition 2-8°C

 Safety Information

RIDADR NONH for all modes of transport

 Synthetic Route

~%

Glycine-2-13C Structure

Glycine-2-13C

CAS#:20220-62-6

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 7 p. 1979 - 1993

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

Glycine-2-C
(2-C)Glycine
MFCD00037550
<C2-13C>glycine
Glycine (2-13C, 99%)
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