TVP1022 (mesylate)

Modify Date: 2025-08-24 22:36:05

TVP1022 (mesylate) Structure
TVP1022 (mesylate) structure
Common Name TVP1022 (mesylate)
CAS Number 202464-88-8 Molecular Weight 267.34400
Density N/A Boiling Point N/A
Molecular Formula C13H17NO3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TVP1022 (mesylate)


TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

 Names

Name S-(-)-N-Propargyl-1-aminoindan mesylate
Synonym More Synonyms

 TVP1022 (mesylate) Biological Activity

Description TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.
Related Catalog
References

[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69.

[2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.

 Chemical & Physical Properties

Molecular Formula C13H17NO3S
Molecular Weight 267.34400
Exact Mass 267.09300
PSA 74.78000
LogP 2.87240
Storage condition 2-8℃

 Synonyms

TVP1022 (mesylate)
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