M-6-G TRIFLUOROACETATE-HYDRATE

Modify Date: 2024-01-13 18:01:41

M-6-G TRIFLUOROACETATE-HYDRATE Structure
M-6-G TRIFLUOROACETATE-HYDRATE structure
Common Name M-6-G TRIFLUOROACETATE-HYDRATE
CAS Number 20290-10-2 Molecular Weight 461.46200
Density 1.64g/cm3 Boiling Point 731.6ºC at 760mmHg
Molecular Formula C23H27NO9 Melting Point 237-240°C (dec.)
MSDS Chinese USA Flash Point 396.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Morphine 6-β-D-Glucuronide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.64g/cm3
Boiling Point 731.6ºC at 760mmHg
Melting Point 237-240°C (dec.)
Molecular Formula C23H27NO9
Molecular Weight 461.46200
Flash Point 396.3ºC
Exact Mass 461.16900
PSA 149.15000
Vapour Pressure 1.8E-22mmHg at 25°C
Index of Refraction 1.731
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ6500700
CHEMICAL NAME :
Glucopyranosiduronic acid, 7,8-didehydro-4,5-alpha-epoxy-3-hydroxy-17-methylmorp hinan-6- alpha-yl-, beta-D-
CAS REGISTRY NUMBER :
20290-10-2
LAST UPDATED :
198909
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H27-N-O9
MOLECULAR WEIGHT :
461.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
432 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67(4),97P,1971

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H317-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases 20/21/22-43
Safety Phrases 36
RIDADR UN 1993C 3 / PGIII
WGK Germany 3
RTECS LZ6500700

 Articles32

More Articles
Morphine glucuronidation increases its analgesic effect in guinea pigs.

Life Sci. 109(2) , 104-10, (2014)

Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-adminis...

[Rapid opiate detoxification under anesthesia (RODA)].

Rev. Med. Liege. 68(5-6) , 298-302, (2013)

Rapid Opiate Detoxification under Anesthesia (RODA) involves the use of opiate antagonists combined with anesthesia and pharmacotherapy to reduce withdrawal symptoms. The aim of our study was to measu...

[Blood-brain barrier transport of opioid analgesics].

Yakugaku Zasshi 131(10) , 1445-51, (2011)

Opioid analgesics exhibit cationic properties under physiological conditions, and the mechanism underlying permeation of the blood-brain barrier thus cannot be fully explained by simple diffusion alon...

 Synonyms

Morphine glucuronide