tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate

Modify Date: 2024-01-17 11:37:59

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure
tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate structure
Common Name tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate
CAS Number 203321-83-9 Molecular Weight 224.25600
Density N/A Boiling Point 316.9 °C at 760 mmHg
Molecular Formula C11H16N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name tert-butyl N-[6-(hydroxymethyl)pyridin-2-yl]carbamate
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 316.9 °C at 760 mmHg
Molecular Formula C11H16N2O3
Molecular Weight 224.25600
Exact Mass 224.11600
PSA 74.94000
LogP 1.93450

 Safety Information

Hazard Codes Xn
HS Code 2933399090

 Synthetic Route

~96%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: Buettelmann, Bernd; Ceccarelli, Simona Maria; Jaeschke, Georg; Kolczewski, Sabine; Porter, Richard Hugh Philip; Vieira, Eric Patent: US2006/160857 A1, 2006 ; Location in patent: Page/Page column 34 ; US 20060160857 A1

~97%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: Majgier-Baranowska, Helena; Li, Bing; Peet, Norton P. Synthetic Communications, 2013 , vol. 43, # 8 p. 1173 - 1180

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: RANBAXY LABORATORIES LIMITED Patent: WO2006/117754 A1, 2006 ; Location in patent: Page/Page column 51 ; WO 2006/117754 A1

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: Mitsuya; Kobayashi; Kawakami; Satoh; Ogino; Kakikawa; Ohtake; Kimura; Hirose; Sato; Numazawa; Hasegawa; Noguchi; Mase Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 5017 - 5029

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: SIRTRIS PHARMACEUTICALS INC.; VU, Chi, B. Patent: WO2011/116176 A1, 2011 ; WO 2011/116176 A1

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: SIRTRIS PHARMACEUTICALS INC.; VU, Chi, B. Patent: WO2011/116176 A1, 2011 ; WO 2011/116176 A1

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank Patent: WO2013/52394 A1, 2013 ;

~%

tert-butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate Structure

tert-butyl (6-(...

CAS#:203321-83-9

Literature: MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank Patent: WO2013/52394 A1, 2013 ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

tert-Butyl (6-(hydroxymethyl)pyridin-2-yl)carbamate
6-tert-butoxycarbonylamino-2-pyridinemethanol
6-tert-butyloxycarbonylaminopyridine-2-methanol
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