Luteollin 5-glucoside

Modify Date: 2025-08-25 18:55:45

Luteollin 5-glucoside Structure
Luteollin 5-glucoside structure
Common Name Luteollin 5-glucoside
CAS Number 20344-46-1 Molecular Weight 448.377
Density 1.7±0.1 g/cm3 Boiling Point 864.2±65.0 °C at 760 mmHg
Molecular Formula C21H20O11 Melting Point 260-263℃
MSDS N/A Flash Point 305.8±27.8 °C

 Use of Luteollin 5-glucoside


Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].

 Names

Name 2-(3,4-dihydroxyphenyl)-7-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym More Synonyms

 Luteollin 5-glucoside Biological Activity

Description Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].
Related Catalog
In Vitro Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages[1].
References

[1]. Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside.Food Chem Toxicol. 2012 Jun;50(6):2171-9.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 864.2±65.0 °C at 760 mmHg
Melting Point 260-263℃
Molecular Formula C21H20O11
Molecular Weight 448.377
Flash Point 305.8±27.8 °C
Exact Mass 448.100555
PSA 190.28000
LogP 0.13
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.740
InChIKey KBGKQZVCLWKUDQ-QNDFHXLGSA-N
SMILES O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(OC3OC(CO)C(O)C(O)C3O)c12

 Safety Information

HS Code 2932999099

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Luteolin-5-O-b-D-glucopyranoside
2-(3,4-Dihydroxyphenyl)-5-(b-D-glucopyranosyloxy)-7-hydroxy-4H-1-benzopyran-4-one
Luteolin-5-O-glucopyranoside
2-(3,4-Dihydroxyphenyl)-7-hydroxy-4-oxo-4H-chromen-5-yl β-D-glucopyranoside
Luteolin-5-O-β-D-glucopyranoside
Luteollin 5-glucoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-(β-D-glucopyranosyloxy)-7-hydroxy-
galuteolin
luteolin 5-O-β-D-glucopyranosyl
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