JNJ-56022486

Modify Date: 2025-07-31 17:03:44

JNJ-56022486 Structure
JNJ-56022486 structure
Common Name JNJ-56022486
CAS Number 2036082-79-6 Molecular Weight 283.72
Density N/A Boiling Point N/A
Molecular Formula C15H10ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JNJ-56022486


A novel potent and selective negative modulator of AMPA receptors containing TARP-gamma8

 Names

Name JNJ-56022486

 JNJ-56022486 Biological Activity

Description A novel potent and selective negative modulator of AMPA receptors containing TARP-gamma8

 Chemical & Physical Properties

Molecular Formula C15H10ClN3O
Molecular Weight 283.72

 JNJ-56022486Bioassay

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Name: Apparent permeability across apical to basolateral side in MDCK-MDR1 cells at 5 uM me...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200551
Name: Apparent permeability across basolateral to apical side in MDCK-MDR1 cells at 5 uM me...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200550
Name: Hepatic extraction ratio in rat liver microsomes at 1 uM measured after 60 mins in pr...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200549
Name: Hepatic extraction ratio in human liver microsomes at 1 uM measured after 60 mins in ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200548
Name: Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F ce...
Source: ChEMBL
Target: Voltage-dependent calcium channel gamma-8 subunit
External Id: CHEMBL4200544
Name: Calcium Flux Assay from US Patent US10611730: "Benzimidazolone and benzothiazolone co...
Source: BindingDB
Target: N/A
External Id: BindingDB_9024_1
Name: Protein binding in rat plasma assessed as unbound fraction at 1 uM measured after 6 h...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200555
Name: Protein binding in human plasma assessed as unbound fraction at 1 uM measured after 6...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4200554
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