K67 structure
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Common Name | K67 | ||
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CAS Number | 2046250-48-8 | Molecular Weight | 582.688 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 752.2±70.0 °C at 760 mmHg | |
Molecular Formula | C29H30N2O7S2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 408.7±35.7 °C |
Use of K67K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2; has specific inhibitory effect on the Nrf2 target genes, dramatically suppresses the proliferations of Huh1 cells and of Huh7 cells expressing phospho-mimetic p62. |
Name | K67 |
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Synonym | More Synonyms |
Description | K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2; has specific inhibitory effect on the Nrf2 target genes, dramatically suppresses the proliferations of Huh1 cells and of Huh7 cells expressing phospho-mimetic p62. |
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References | References 1. Saito T, et al. Nat Commun. 2016 Jun 27;7:12030. View Related Products by Target Keap1-Nrf2 |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 752.2±70.0 °C at 760 mmHg |
Molecular Formula | C29H30N2O7S2 |
Molecular Weight | 582.688 |
Flash Point | 408.7±35.7 °C |
Exact Mass | 582.149414 |
LogP | 5.09 |
Vapour Pressure | 0.0±2.5 mmHg at 25°C |
Index of Refraction | 1.640 |
N,N'-[2-(2-Oxopropyl)naphthalene-1,4-Diyl]bis(4-Ethoxybenzenesulfonamide) |
2-Acetonyl-1,4-bis[(4-ethoxybenzensulfonyl)amino]naphthalene |
N,N'-(2-(2-Oxopropyl)naphthalene-1,4-diyl)bis(4-ethoxybenzenesulfonamide) |
Benzenesulfonamide, N,N'-[2-(2-oxopropyl)-1,4-naphthalenediyl]bis[4-ethoxy- |
N,N'-[2-(2-Oxopropyl)-1,4-naphthalenediyl]bis(4-ethoxybenzenesulfonamide) |
K67 |
N-[2-Acetonyl-4-(4-ethoxybenzenesulfonylamino)naphthalene-1-yl]-4-ethoxybenzenesulfonamide |