Benz[j]fluoranthene

registration deadline.
Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Carcinogenicity (Category 1B), H350
Specific target organ toxicity - single exposure (Category 3), Respiratory system, Central nervous system,
H335, H336
Specific target organ toxicity - repeated exposure, Oral (Category 2), Liver, Blood, H373
Specific target organ toxicity - repeated exposure, Inhalation (Category 2), Central nervous system, H373
Chronic aquatic toxicity (Category 3), H412
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
T ToxicR45
R67, R36/37/38
R52/53
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal wordDanger
Hazard statement(s)
H315Causes skin irritation.
H319Causes serious eye irritation.
H335May cause respiratory irritation.
H336May cause drowsiness or dizziness.
H350May cause cancer.
H373May cause damage to organs (Liver, Blood) through prolonged or
repeated exposure if swallowed.
H373May cause damage to organs (Central nervous system) through
prolonged or repeated exposure if inhaled.
H412Harmful to aquatic life with long lasting effects.
Precautionary statement(s)
P201Obtain special instructions before use.
P261Avoid breathing vapours.
P273Avoid release to the environment.
P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P308 + P313IF exposed or concerned: Get medical advice/ attention.
Supplemental Hazardnone
Statements
Restricted to professional users.
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)T Toxic
R-phrase(s)
R45May cause cancer.
R36/37/38Irritating to eyes, respiratory system and skin.
R52/53Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
R67Vapours may cause drowsiness and dizziness.
S-phrase(s)
S53Avoid exposure - obtain special instructions before use.
S26In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S45In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
S61Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Restricted to professional users.
Other hazards - none

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SECTION 3: Composition/information on ingredients
Mixtures
Formula: C20H12
Molecular Weight: 252,31 g/mol
Hazardous ingredients according to Regulation (EC) No 1272/2008
ComponentClassificationConcentration
Methylene chloride
CAS-No.75-09-2Skin Irrit. 2; Eye Irrit. 2; Carc.<= 100 %
EC-No.200-838-92; STOT SE 3; STOT RE 2;
Index-No.602-004-00-3H315, H319, H335, H336,
H351, H373, H373
Benz(j)fluoranthene
CAS-No.205-82-3Carc. 1B; Aquatic Acute 1;0,1 - 0,25 %
EC-No.205-910-3Aquatic Chronic 1; H350,
Index-No.601-035-00-XH410
Hazardous ingredients according to Directive 1999/45/EC
ComponentClassificationConcentration
Methylene chloride
CAS-No.75-09-2Xn, Carc.Cat.3, Xi, R36/37/38 <= 100 %
EC-No.200-838-9- R40 - R67
Index-No.602-004-00-3
Benz(j)fluoranthene
CAS-No.205-82-3T, N, Carc.Cat.2, R45 -0,1 - 0,25 %
EC-No.205-910-3R50/53
Index-No.601-035-00-X
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Hydrogen chloride gas
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Evacuate personnel to safe areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.Avoid exposure - obtain special
instructions before use.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Heat sensitive.
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) AppearanceForm: liquid
b) Odourno data available
c) Odour Thresholdno data available
d) pHno data available
e) Melting point/freezingno data available
point
f) Initial boiling point and 40,0 °C at 1.013,2 hPa
boiling range
g) Flash pointno data available
h) Evapouration rateno data available
i) Flammability (solid, gas) no data available
j) Upper/lowerno data available
flammability or
explosive limits
k) Vapour pressure470,9 hPa at 20,0 °C
l) Vapour densityno data available
m) Relative densityno data available
n) Water solubilityslightly soluble
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignitionno data available
temperature
q) Decompositionno data available
temperature
r) Viscosityno data available
s) Explosive propertiesno data available
t) Oxidizing propertiesno data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Bases, Alkali metals, Strong acids and strong bases, Strong oxidizing agents, Amines, Vinyl compounds,
Aluminum, Magnesium
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC:2B - Group 2B: Possibly carcinogenic to humans (Methylene chloride)
IARC:2B - Group 2B: Possibly carcinogenic to humans (Benz(j)fluoranthene)
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
Inhalation - May cause damage to organs through prolonged or repeated exposure. - Central nervous
system
Oral - May cause damage to organs through prolonged or repeated exposure. - Liver, Blood
Aspiration hazard
no data available
Additional Information
RTECS: Not available
Dichloromethane is metabolized in the body producing carbon monoxide which increases and sustains
carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a
simple asphyxiant by displacing air., anesthetic effects, Breathing difficulties, Headache, Dizziness,
Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:,
Redness, Blurred vision, Provokes tears.

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SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
Harmful to aquatic life with long lasting effects.

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: 1593IMDG: 1593IATA: 1593
UN proper shipping name
ADR/RID: DICHLOROMETHANE, SOLUTION
IMDG: DICHLOROMETHANE, SOLUTION
IATA:Dichloromethane, SOLUTION
Transport hazard class(es)
ADR/RID: 6.1IMDG: 6.1IATA: 6.1
Packaging group
ADR/RID: IIIIMDG: IIIIATA: III
Environmental hazards
ADR/RID: noIMDG Marine pollutant: noIATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

DATA ITEMS CITED :

18

MOLECULAR FORMULA :

C20-H12

MOLECULAR WEIGHT :

252.32

WISWESSER LINE NOTATION :

L D6 C6566 1A TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Implant

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

25 mg/kg

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

312 mg/kg/26W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

11102 ug/kg/15D-I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Implant

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

3760 nmol/kg

REFERENCE :

PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 25,121,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,82,1973 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,155,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,155,1983 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0465 No. of Facilities: 142 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 2283 (estimated)