6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

Modify Date: 2024-01-23 13:23:22

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine structure	Common Name	6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine
	CAS Number	205171-04-6	Molecular Weight	613.02
	Density	1.41	Boiling Point	757.022ºC at 760 mmHg
	Molecular Formula	C₃₂H₂₅ClN₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine dibenzoate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine
Synonym	More Synonyms

Description	6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine dibenzoate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.41
Boiling Point	757.022ºC at 760 mmHg
Molecular Formula	C₃₂H₂₅ClN₄O₇
Molecular Weight	613.02
Exact Mass	612.14100
PSA	131.73000
LogP	5.07540
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.667

6-chloropurine

CAS#:87-42-3

(2S,3R,4R,5R)-2...

CAS#:15397-15-6

~99%

6-Chloro-9-(2,3...

CAS#:205171-04-6

Literature: Bio, Matthew M.; Xu, Feng; Waters, Marjorie; Williams, J. Michael; Savary, Kimberly A.; Cowden, Cameron J.; Yang, Chunhua; Buck, Elizabeth; Song, Zhiguo J.; Tschaen, David M.; Volante; Reamer, Robert A.; Grabowski, Edward J. J. Journal of Organic Chemistry, 2004 , vol. 69, # 19 p. 6257 - 6266

Precursor 2
CAS#:87-42-3 6-chloropurine CAS#:15397-15-6 (2S,3R,4R,5R)-2...
DownStream 3
CAS#:15397-12-3 2'-C-Methyladenosine CAS#:205171-05-7 6-Chloro-9-(2-C... CAS#:172722-76-8 2'-C-Methyl-6-S...

(2R,3R,4R,5R)-5-[(benzoyloxy)methyl]-2-(6-chloro-9H-purin-9-yl)-3-methyltetrahydrofuran-3,4-diyl dibenzoate

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

Use of 6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl)-9H-purine

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