azido-tris(ethylenoxy)-L-alanine TFA

Modify Date: 2024-01-21 12:46:15

azido-tris(ethylenoxy)-L-alanine TFA Structure
azido-tris(ethylenoxy)-L-alanine TFA structure
 Common Name azido-tris(ethylenoxy)-L-alanine TFA
CAS Number 2054345-67-2 Molecular Weight 262.26
Density N/A Boiling Point N/A
Molecular Formula C9H18N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of azido-tris(ethylenoxy)-L-alanine TFA


Azide-PEG3-C1-Ala is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG3-C1-Ala

 azido-tris(ethylenoxy)-L-alanine TFA Biological Activity

Description Azide-PEG3-C1-Ala is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H18N4O5
Molecular Weight 262.26
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