N-Boc-Azido-tris(ethylenoxy)-L-alanine

Modify Date: 2024-01-24 18:41:20

N-Boc-Azido-tris(ethylenoxy)-L-alanine Structure
N-Boc-Azido-tris(ethylenoxy)-L-alanine structure
Common Name N-Boc-Azido-tris(ethylenoxy)-L-alanine
CAS Number 2054345-68-3 Molecular Weight 362.38
Density N/A Boiling Point N/A
Molecular Formula C14H26N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Boc-Azido-tris(ethylenoxy)-L-alanine


Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-Ala-Boc

 N-Boc-Azido-tris(ethylenoxy)-L-alanine Biological Activity

Description Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H26N4O7
Molecular Weight 362.38