N-Me-N-(PEG4-acid)2

Modify Date: 2024-01-08 20:08:58

N-Me-N-(PEG4-acid)2 Structure
N-Me-N-(PEG4-acid)2 structure
Common Name N-Me-N-(PEG4-acid)2
CAS Number 2055014-77-0 Molecular Weight 527.60
Density N/A Boiling Point N/A
Molecular Formula C23H45NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Me-N-(PEG4-acid)2


N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Me-N-bis(PEG4-acid)
Synonym More Synonyms

 N-Me-N-(PEG4-acid)2 Biological Activity

Description N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H45NO12
Molecular Weight 527.60

 Synonyms

MFCD28976691