Bis-PEG10-acid

Modify Date: 2024-01-10 10:41:18

Bis-PEG10-acid Structure
Bis-PEG10-acid structure
Common Name Bis-PEG10-acid
CAS Number 2055023-26-0 Molecular Weight 558.61
Density N/A Boiling Point N/A
Molecular Formula C24H46O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG10-acid


Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG10-acid

 Bis-PEG10-acid Biological Activity

Description Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298.

 Chemical & Physical Properties

Molecular Formula C24H46O14
Molecular Weight 558.61