LAU159

Modify Date: 2024-01-14 21:38:02

LAU159 Structure
LAU159 structure
Common Name LAU159
CAS Number 2055050-87-6 Molecular Weight 325.749
Density 1.5±0.1 g/cm3 Boiling Point 473.8±55.0 °C at 760 mmHg
Molecular Formula C17H12ClN3O2 Melting Point N/A
MSDS N/A Flash Point 240.3±31.5 °C

 Use of LAU159


LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].

 Names

Name LAU159
Synonym More Synonyms

 LAU159 Biological Activity

Description LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].
Related Catalog
Target

EC50: 2.2 μM (α1β3 GABA(A) receptor)[1]

References

[1]. Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169(2):371-83.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 473.8±55.0 °C at 760 mmHg
Molecular Formula C17H12ClN3O2
Molecular Weight 325.749
Flash Point 240.3±31.5 °C
Exact Mass 325.061798
LogP 3.16
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.706

 Synonyms

8-Chloro-2-(3-methoxyphenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one