PC-Biotin-PEG4-NHS carbonate

Modify Date: 2025-08-27 10:11:42

PC-Biotin-PEG4-NHS carbonate Structure
PC-Biotin-PEG4-NHS carbonate structure
Common Name PC-Biotin-PEG4-NHS carbonate
CAS Number 2055198-03-1 Molecular Weight 810.87
Density N/A Boiling Point N/A
Molecular Formula C35H50N6O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PC-Biotin-PEG4-NHS carbonate


PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PC-Biotin-PEG4-NHS carbonate

 PC-Biotin-PEG4-NHS carbonate Biological Activity

Description PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C35H50N6O14S
Molecular Weight 810.87
InChIKey APFWBUQXFFFWPE-WMEVZKCTSA-N
SMILES CC(OC(=O)ON1C(=O)CCC1=O)c1cc(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC2SCC3NC(=O)NC32)ccc1[N+](=O)[O-]
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