HPK1-IN-2

Modify Date: 2023-01-14 15:27:32

HPK1-IN-2 Structure
HPK1-IN-2 structure
Common Name HPK1-IN-2
CAS Number 2056122-11-1 Molecular Weight 380.47
Density N/A Boiling Point N/A
Molecular Formula C19H20N6Os Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HPK1-IN-2


HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.

 Names

Name HPK1-IN-2

 HPK1-IN-2 Biological Activity

Description HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.

 Chemical & Physical Properties

Molecular Formula C19H20N6Os
Molecular Weight 380.47
Storage condition -20°C
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