L-R4W2

Modify Date: 2024-04-03 17:05:00

L-R4W2 structure	Common Name	L-R4W2
	CAS Number	206350-79-0	Molecular Weight	1015.18000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₇₁N₂₁O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of L-R4W2

L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic[1][2].

Name	l-r4w2
Synonym	More Synonyms

Description	L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	TRPV1:0.1 μM (IC50)
References	[1]. Planells-Cases R, et, al. Arginine-rich peptides are blockers of VR-1 channels with analgesic activity. FEBS Lett. 2000 Sep 15; 481(2): 131-6. [2]. Himmel HM, et, al. The arginine-rich hexapeptide R4W2 is a stereoselective antagonist at the vanilloid receptor 1: a Ca2+ imaging study in adult rat dorsal root ganglion neurons. J Pharmacol Exp Ther. 2002 Jun; 301(3): 981-6.

Molecular Formula	C₄₆H₇₁N₂₁O₆
Molecular Weight	1015.18000
Exact Mass	1014.57000
PSA	488.00000
LogP	4.74190

MFCD03791319

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China
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China
Product Name: L-R4W2
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