TNF-α-IN-2

Modify Date: 2025-08-25 14:04:25

TNF-α-IN-2 Structure
TNF-α-IN-2 structure
Common Name TNF-α-IN-2
CAS Number 2074702-04-6 Molecular Weight 494.92
Density N/A Boiling Point N/A
Molecular Formula C25H21ClF2N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNF-α-IN-2


TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis.

 Names

Name TNF-α-IN-2

 TNF-α-IN-2 Biological Activity

Description TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis.

 Chemical & Physical Properties

Molecular Formula C25H21ClF2N6O
Molecular Weight 494.92
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