TNF-α-IN-2 structure
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Common Name | TNF-α-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 2074702-04-6 | Molecular Weight | 494.92 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H21ClF2N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TNF-α-IN-2TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis. |
| Name | TNF-α-IN-2 |
|---|
| Description | TNF-α-IN-2 is a potent and orally active of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis. |
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| Molecular Formula | C25H21ClF2N6O |
|---|---|
| Molecular Weight | 494.92 |