Cyclo(-Trp-Trp)

Modify Date: 2025-08-27 20:38:18

Cyclo(-Trp-Trp) structure	Common Name	Cyclo(-Trp-Trp)
	CAS Number	20829-55-4	Molecular Weight	372.420
	Density	1.4±0.1 g/cm3	Boiling Point	813.4±60.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₀N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	445.7±32.9 °C

Use of Cyclo(-Trp-Trp)

Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1].

Name	(3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione
Synonym	More Synonyms

Description	Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Cyclo(L-Trp-L-Trp) can inhibit A. baumannii (MICs=12.5-25 µg/mL), as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus (MICs=12.5-50 µg/mL)[1].
References	[1]. Keyong Ho Lee, et al. Identification of Streptomyces sp. KH29, which produces an antibiotic substance processing an inhibitory activity against multidrug-resistant Acinetobacter baumannii. J Microbiol Biotechnol. 2010 Dec;20(12):1672-6.

Density	1.4±0.1 g/cm3
Boiling Point	813.4±60.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₀N₄O₂
Molecular Weight	372.420
Flash Point	445.7±32.9 °C
Exact Mass	372.158630
PSA	89.78000
LogP	1.66
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.724
InChIKey	DNHODRZUCGXYKU-PMACEKPBSA-N
SMILES	O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1c[nH]c2ccccc12

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Cytotoxicity against human cisplatin resistant A2780 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: A2780
External Id: CHEMBL2032599

Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist

Name: Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E...
Source: NCGC
External Id: epac1-activator-v

Name: Cytotoxicity against human K562 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: K562
External Id: CHEMBL2032597

Name: Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3...
Source: NCGC
External Id: epac1-inhibitor-v

Name: Cytotoxicity against human cisplatin sensitive A2780 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: A2780
External Id: CHEMBL2032598

Name: Partition coefficient, log P of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL905620

Name: Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E...
Source: NCGC
External Id: epac2-activator-v2

Name: Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4...
Source: NCGC
External Id: epac2-inhibitor-v2

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100

Total 19, Current Page 1 of 2

cyclo-(L-Trp-L-Trp)

cyclo(L-tryptophanyl-L-tryptophanyl)

cyclo(tryptophyl-tryptophyl)

Cyclo(L-Trp-L-Trp)

Fellutanine A

(3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione

(3S,6S)-3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione

c-(L-Trp-L-Trp)

3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione

cyclo-L-tryptophan-L-tryptophan

cyclo(Trp-Trp)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclo(L-Trp-L-Trp)
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CYCLO(-TRP-TRP)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.