BI-8668

Modify Date: 2024-04-08 06:36:18

BI-8668 Structure
BI-8668 structure
Common Name BI-8668
CAS Number 2084059-97-0 Molecular Weight 523.463
Density N/A Boiling Point N/A
Molecular Formula C23H32Cl2N8O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-8668


BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM.

 Names

Name BI-8668

 BI-8668 Biological Activity

Description BI-8668 (BI 8668) is a highly potent and selective epithelial sodium channel (ENaC) inhibitor, inhibits Na+ current with IC50 of 17 nM (Ussing chamber assay);BI-8668 inhibits ENaC-mediated water permeability through cell monolayers of the cell line M-1 (M-1 cells: mouse kidney tubules cells) with 81% inhibition at 3 uM.

 Chemical & Physical Properties

Molecular Formula C23H32Cl2N8O2
Molecular Weight 523.463
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