Epothilone F

Modify Date: 2024-01-05 12:53:19

Epothilone F Structure
Epothilone F structure
Common Name Epothilone F
CAS Number 208518-52-9 Molecular Weight 523.68200
Density N/A Boiling Point N/A
Molecular Formula C27H41NO7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Epothilone F


Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells, drug-resistant ovarian cancer cells[1].

 Names

Name Epothilone F
Synonym More Synonyms

 Epothilone F Biological Activity

Description Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells, drug-resistant ovarian cancer cells[1].
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References

[1]. Flörsheimer A, et al. Epothilones and their analogues-a new class of promising microtubule inhibitors[J]. Expert Opinion on Therapeutic Patents, 2001, 11(6): 951-968.

 Chemical & Physical Properties

Molecular Formula C27H41NO7S
Molecular Weight 523.68200
Exact Mass 523.26000
PSA 157.72000
LogP 3.66140

 Synonyms

epothilone F
(1S,3S(E),7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione
(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-3-[(E)-2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione
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