Tz-Thalidomide

Modify Date: 2024-04-03 18:46:15

Tz-Thalidomide structure	Common Name	Tz-Thalidomide
	CAS Number	2087490-42-2	Molecular Weight	571.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₉N₇O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tz-Thalidomide

Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2)[1].

Name	6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)hexanamide

Description	Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	46.25 μM (BRD4-1), 62.55 μM (BRD4-2)[1]
References	[1]. Lebraud H, et al. Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras. ACS Cent Sci. 2016 Dec 28;2(12):927-934.

Molecular Formula	C₂₉H₂₉N₇O₆
Molecular Weight	571.58

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tz-Thalidomide
Price: Check
Purity: 98.34%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

Tz-Thalidomide suppliers

Price: ￥1600/5 mg

Reference only. check more Tz-Thalidomide price

Tz-Thalidomide

Use of Tz-Thalidomide

Names

Tz-Thalidomide Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.