Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]

Name: Solubility of compound in PBS at pH 7.4 after 24 hrs
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324289

Name: 1-Octanol-PBS buffer distribution coefficient, log D of compound at pH 7.4
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324288

Name: Inhibition of ERK1/2 in human A375 cells assessed as inhibition of RSK phosphorylatio...
Source: ChEMBL
Target: Mitogen-activated protein kinase 3
External Id: CHEMBL4324287

Name: Inhibition of ERK1/2 in human A375 cells assessed as inhibition of ERK phosphorylatio...
Source: ChEMBL
Target: Mitogen-activated protein kinase 3
External Id: CHEMBL4324286

Name: Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate pre...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL4324285

Name: Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate pre...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL4324284

Name: Clearance in human liver microsomes measured per mg of protein
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324283

Name: Inhibition of human ERG
Source: ChEMBL
Target: Potassium voltage-gated channel subfamily H member 2
External Id: CHEMBL4324297

Name: Apparent permeability across apical to basolateral side in human Caco2 cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324296

Name: Intrinsic clearance in human hepatocytes measured per million of cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324295