Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]
Modify Date: 2026-07-02 18:34:53
![Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] Structure](https://www.chemsrc.com/extcaspic/289/2097416-92-5.png)
Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] structure
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Common Name | Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] | ||
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| CAS Number | 2097416-92-5 | Molecular Weight | 450.4 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H20F2N8O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] |
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This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C22H20F2N8O |
|---|---|
| Molecular Weight | 450.4 |
| InChIKey | GGHDHMVFBOLCFR-UHFFFAOYSA-N |
| SMILES | Cc1cnc(Nc2ccnn2C)nc1-c1cn2c(n1)C(=O)N(Cc1ccc(F)c(F)c1)CC2 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Solubility of compound in PBS at pH 7.4 after 24 hrs
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324289
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Name: 1-Octanol-PBS buffer distribution coefficient, log D of compound at pH 7.4
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324288
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Name: Inhibition of ERK1/2 in human A375 cells assessed as inhibition of RSK phosphorylatio...
Source: ChEMBL
Target: Mitogen-activated protein kinase 3
External Id: CHEMBL4324287
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Name: Inhibition of ERK1/2 in human A375 cells assessed as inhibition of ERK phosphorylatio...
Source: ChEMBL
Target: Mitogen-activated protein kinase 3
External Id: CHEMBL4324286
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Name: Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate pre...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL4324285
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Name: Inhibition of MEK U911-activated ERK2 (unknown origin) using ERKtide as substrate pre...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL4324284
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Name: Clearance in human liver microsomes measured per mg of protein
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324283
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Name: Inhibition of human ERG
Source: ChEMBL
Target: Potassium voltage-gated channel subfamily H member 2
External Id: CHEMBL4324297
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Name: Apparent permeability across apical to basolateral side in human Caco2 cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324296
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Name: Intrinsic clearance in human hepatocytes measured per million of cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL4324295
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This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: CAS number of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is 2097416-92-5. |
| Q: What is the InChIKey of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: InChIKey of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is GGHDHMVFBOLCFR-UHFFFAOYSA-N. |
| Q: What is the molecular weight of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: Molecular weight of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is 450.4. |
| Q: What is the Chinese name of 2097416-92-5? |
| A: Chinese name of 2097416-92-5 is 2097416-92-5. |
| Q: What is the English name of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: The English name of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]. |
| Q: What is the SMILES notation of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: SMILES notation of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is Cc1cnc(Nc2ccnn2C)nc1-c1cn2c(n1)C(=O)N(Cc1ccc(F)c(F)c1)CC2. |
| Q: What is the molecular formula of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]? |
| A: Molecular formula of Imidazo[1,2-a]pyrazin-8(5H)-one, 7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl] is C22H20F2N8O. |