Anticancer agent 109 structure
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Common Name | Anticancer agent 109 | ||
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| CAS Number | 2097497-16-8 | Molecular Weight | 317.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H15N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Anticancer agent 109Anticancer agent 109 (compound 6-15) is an inhibitor of the Gas6-Axl axis with anti-cancer activity. Anticancer agent 109 inhibits the expression of Gas6 and Axl, and the expression p-PI3K and p-AKT in cancer cells, leads to G1 phase arrest and promotes cancer cells apoptosis, and inhibits tumor growth significantly in nude mouse tumor bearing models[1]. |
| Name | Anticancer agent 109 |
|---|
| Description | Anticancer agent 109 (compound 6-15) is an inhibitor of the Gas6-Axl axis with anti-cancer activity. Anticancer agent 109 inhibits the expression of Gas6 and Axl, and the expression p-PI3K and p-AKT in cancer cells, leads to G1 phase arrest and promotes cancer cells apoptosis, and inhibits tumor growth significantly in nude mouse tumor bearing models[1]. |
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| Related Catalog | |
| Target |
Axl |
| References |
| Molecular Formula | C19H15N3O2 |
|---|---|
| Molecular Weight | 317.34 |