rel-Zotatifin
Modify Date: 2024-04-05 01:06:01
rel-Zotatifin structure
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Common Name | rel-Zotatifin | ||
|---|---|---|---|---|
| CAS Number | 2098191-54-7 | Molecular Weight | 487.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H29N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of rel-Zotatifinrel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex. |
| Name | rel-Zotatifin |
|---|
| Description | rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex. |
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| Molecular Formula | C28H29N3O5 |
|---|---|
| Molecular Weight | 487.55 |