2098191-54-7
2098191-54-7 structure
- Name: rel-Zotatifin
- Chemical Name: rel-Zotatifin
- CAS Number: 2098191-54-7
- Molecular Formula: C28H29N3O5
- Molecular Weight: 487.55
- Create Date: 2021-08-10 15:34:43
- Modify Date: 2024-04-05 01:06:01
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rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.
| Name | rel-Zotatifin |
|---|
| Description | rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex. |
|---|
| Molecular Formula | C28H29N3O5 |
|---|---|
| Molecular Weight | 487.55 |