AT-127
Modify Date: 2025-08-24 23:03:58
AT-127 structure
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Common Name | AT-127 | ||
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| CAS Number | 2099680-72-3 | Molecular Weight | 369.509 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H31N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AT-127AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM; displays >60-fold selectivity over mu and kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists. |
| Name | AT-127 |
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| Description | AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM; displays >60-fold selectivity over mu and kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists. |
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| References | References 1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13. View Related Products by Target Opioid Receptor |
| Molecular Formula | C22H31N3O2 |
|---|---|
| Molecular Weight | 369.509 |
| InChIKey | XQBNAHDJKLRKQK-UHFFFAOYSA-N |
| SMILES | CC(C)C1CCC(N2CCC(n3c(O)c(N=O)c4ccccc43)CC2)CC1 |