N-Mal-N-bis(PEG2-t-butyl ester)

Modify Date: 2024-01-02 18:30:36

N-Mal-N-bis(PEG2-t-butyl ester) Structure
N-Mal-N-bis(PEG2-t-butyl ester) structure
Common Name N-Mal-N-bis(PEG2-t-butyl ester)
CAS Number 2100306-51-0 Molecular Weight 600.70
Density N/A Boiling Point N/A
Molecular Formula C29H48N2O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Mal-N-bis(PEG2-t-butyl ester)


N-Mal-N-bis(PEG2-C2-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Mal-N-bis(PEG2-C2-Boc)
Synonym More Synonyms

 N-Mal-N-bis(PEG2-t-butyl ester) Biological Activity

Description N-Mal-N-bis(PEG2-C2-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H48N2O11
Molecular Weight 600.70

 Synonyms

MFCD29912830
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