N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

Modify Date: 2025-08-27 01:48:20

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) structure	Common Name	N-Desthiobiotin-N-bis(PEG4-t-butyl ester)
	CAS Number	2353409-60-4	Molecular Weight	822.04
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₇₅N₃O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

Description	N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₀H₇₅N₃O₁₄
Molecular Weight	822.04
InChIKey	PUELEIRDQBMWBK-SZAHLOSFSA-N
SMILES	CC1NC(=O)NC1CCCCCC(=O)N(CCOCCOCCOCCOCCC(=O)OC(C)(C)C)CCOCCOCCOCCOCCC(=O)OC(C)(C)C

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