RAD51-IN-17

Modify Date: 2024-09-19 19:21:18

RAD51-IN-17 Structure
RAD51-IN-17 structure
Common Name RAD51-IN-17
CAS Number 2101739-18-6 Molecular Weight 373.84
Density N/A Boiling Point N/A
Molecular Formula C22H16ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RAD51-IN-17


RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers.

 Names

Name RAD51-IN-17

 RAD51-IN-17 Biological Activity

Description RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers.
References References 1. Ward A, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. View Related Products by Target DNA Repair Protein

 Chemical & Physical Properties

Molecular Formula C22H16ClN3O
Molecular Weight 373.84
Storage condition -20°C
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