RAD51-IN-17
Modify Date: 2024-09-19 19:21:18
RAD51-IN-17 structure
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Common Name | RAD51-IN-17 | ||
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| CAS Number | 2101739-18-6 | Molecular Weight | 373.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H16ClN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RAD51-IN-17RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers. |
| Name | RAD51-IN-17 |
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| Description | RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers. |
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| References | References 1. Ward A, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. View Related Products by Target DNA Repair Protein |
| Molecular Formula | C22H16ClN3O |
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| Molecular Weight | 373.84 |
| Storage condition | -20°C |