2-Thiazolamine,4-(4-methylphenyl)

Modify Date: 2026-07-14 07:00:50

2-Thiazolamine,4-(4-methylphenyl) Structure
2-Thiazolamine,4-(4-methylphenyl) structure
 Common Name 2-Thiazolamine,4-(4-methylphenyl)
CAS Number 2103-91-5 Molecular Weight 190.26500
Density 1.219g/cm3 Boiling Point 369.4ºC at 760mmHg
Molecular Formula C10H10N2S Melting Point 132-136 °C(lit.)
MSDS Chinese USA Flash Point 177.2ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-amino-4-(p-tolyl)thiazole
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.219g/cm3
Boiling Point 369.4ºC at 760mmHg
Melting Point 132-136 °C(lit.)
Molecular Formula C10H10N2S
Molecular Weight 190.26500
Flash Point 177.2ºC
Exact Mass 190.05600
PSA 67.15000
LogP 3.28190
Vapour Pressure 1.19E-05mmHg at 25°C
Index of Refraction 1.642
InChIKey ARLHWYFAPHJCJT-UHFFFAOYSA-N
SMILES Cc1ccc(-c2csc(N)n2)cc1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R20/21/22
Safety Phrases S26-S36/37
RIDADR 2811
WGK Germany 3
Packaging Group III
Hazard Class 6.1
HS Code 2934100090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

thiourea structure

thiourea

CAS#:17356-08-0

2-bromo-4'-methylacetophenone structure

2-bromo-4'-meth...

CAS#:619-41-0

~98%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: TAIVEX THERAPEUTICS CORPORATION; HUANG, Yu-Ling; CHUANG, Shih-Hsien; LEE, Ying-Shuan Eda; HUANG, Jiann-Jyh; LAU, Johnson Patent: WO2013/82324 A1, 2013 ; Location in patent: Paragraph 00265 ;
thiourea structure

thiourea

CAS#:17356-08-0

4'-Methylacetophenone structure

4'-Methylacetop...

CAS#:122-00-9

~78%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Caceres-Castillo, David; Carballo, Ruben M.; Tzec-Interian, Jorge A.; Mena-Rejon, Gonzalo J. Tetrahedron Letters, 2012 , vol. 53, # 30 p. 3934 - 3936
4'-Methylacetophenone structure

4'-Methylacetop...

CAS#:122-00-9

~55%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: SAWAI PHARMACEUTICAL CO., LTD. Patent: EP321115 B1, 1991 ;
3,4-dichloro-4-phenyl-butan-2-one structure

3,4-dichloro-4-...

CAS#:40805-62-7

thiourea structure

thiourea

CAS#:17356-08-0

~%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Tetrahedron, , vol. 68, # 1 p. 173 - 178
thiourea structure

thiourea

CAS#:17356-08-0

(Z)-2-diazonio-1-(4-methylphenyl)ethenolate structure

(Z)-2-diazonio-...

CAS#:17263-64-8

~96%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Yadav; Reddy, B.V. Subba; Rao, Y. Gopala; Narsaiah Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2381 - 2383
2,2-Dibromo-4'-methylacetophenone structure

2,2-Dibromo-4'-...

CAS#:13664-98-7

thiourea structure

thiourea

CAS#:17356-08-0

~%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Tetrahedron Letters, , vol. 53, # 30 p. 3835 - 3838
[2-(4-methylphenyl)-2-oxoethyl] 4-methylbenzenesulfonate structure

[2-(4-methylphe...

CAS#:98475-04-8

thiourea structure

thiourea

CAS#:17356-08-0

~82%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Kumar, V. Pavan; Narender; Sridhar; Nageswar; Rao, K. Rama Synthetic Communications, 2007 , vol. 37, # 24 p. 4331 - 4336
4-Ethynyltoluene structure

4-Ethynyltoluene

CAS#:766-97-2

~%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Tetrahedron Letters, , vol. 53, # 30 p. 3835 - 3838
thiourea structure

thiourea

CAS#:17356-08-0

~%

2-Thiazolamine,4-(4-methylphenyl) Structure

2-Thiazolamine,...

CAS#:2103-91-5

Learn More
Literature: Synthetic Communications, , vol. 40, # 3 p. 391 - 399

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 2-Thiazolamine,4-(4-methylphenyl)Bioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Binding affinity to Plasmodium falciparum AMA1 at 200 uM by surface plasmon resonance...
Source: ChEMBL
Target: Apical membrane antigen 1
External Id: CHEMBL3414329
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: uHTS identification of small molecule modulators of NR3A
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A1015-NR3A-Primary-Assay
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

IFLAB-BB F0777-0809
AURORA 5316
4-(p-Tolyl)-2-thiazolamine
2-Amino-4-(4-methylphenyl)thiazole
2-amino-4-(p-tolyl)-thiazole
2-amino-4-p-methylphenylthiazole
2-Amino-4-(p-tolyl)thiazole
4-P-TOLYL-THIAZOL-2-YLAMINE
4-(4-methylphenyl)-2-thiazolamine
4-(4-methylphenyl)-1,3-thiazol-2-amine
MFCD00170264
4-P-TOLYLTHIAZOL-2-AMINE
2-amino-4(4'-methylphenyl)-thiazole

 2-Thiazolamine,4-(4-methylphenyl) | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the upstream materials of 2-amino-4-(p-tolyl)thiazole?
A: Related upstream materials(CAS) of 2-amino-4-(p-tolyl)thiazole: 619-41-0;122-00-9;40805-62-7;17263-64-8;13664-98-7;98475-04-8;766-97-2.
Q: What is the LogP of 2-amino-4-(p-tolyl)thiazole?
A: LogP of 2-amino-4-(p-tolyl)thiazole is 3.28190.
Q: What is the boiling point of 2-amino-4-(p-tolyl)thiazole?
A: Boiling point of 2-amino-4-(p-tolyl)thiazole is 369.4ºC at 760mmHg.
Q: What is the safety information for 2-amino-4-(p-tolyl)thiazole?
A: Safety information for 2-amino-4-(p-tolyl)thiazole: S26-S36/37.
Q: What is the English name of 2-amino-4-(p-tolyl)thiazole?
A: The English name of 2-amino-4-(p-tolyl)thiazole is 2-amino-4-(p-tolyl)thiazole.
Q: What is the molecular weight of 2-amino-4-(p-tolyl)thiazole?
A: Molecular weight of 2-amino-4-(p-tolyl)thiazole is 190.26500.
Q: What are the downstream products of 2-amino-4-(p-tolyl)thiazole?
A: Related downstream products(CAS) of 2-amino-4-(p-tolyl)thiazole: 6081-87-4;2982-87-8;103966-01-4;72307-67-6;67948-20-3;67948-21-4;89405-35-6;53101-17-0;6122-09-4;6122-27-6.
Q: What is the CAS number of 2-amino-4-(p-tolyl)thiazole?
A: CAS number of 2-amino-4-(p-tolyl)thiazole is 2103-91-5.
Q: What is the InChIKey of 2-amino-4-(p-tolyl)thiazole?
A: InChIKey of 2-amino-4-(p-tolyl)thiazole is ARLHWYFAPHJCJT-UHFFFAOYSA-N.
Q: What is the polar surface area (PSA) of 2-amino-4-(p-tolyl)thiazole?
A: Polar surface area (PSA) of 2-amino-4-(p-tolyl)thiazole is 67.15000.

 2-Thiazolamine,4-(4-methylphenyl)factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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