2’,3’,5’-Tri-O-benzoyl-2-thiouridine

Modify Date: 2024-01-04 17:58:46

2’,3’,5’-Tri-O-benzoyl-2-thiouridine structure	Common Name	2’,3’,5’-Tri-O-benzoyl-2-thiouridine
	CAS Number	21052-18-6	Molecular Weight	572.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₄N₂O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2’,3’,5’-Tri-O-benzoyl-2-thiouridine

2’,3’,5’-Tri-O-benzoyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2,3,5,-Tri-O-benzoyl-2-thiouridine
Synonym	More Synonyms

Description	2’,3’,5’-Tri-O-benzoyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₃₀H₂₄N₂O₈S
Molecular Weight	572.59
Exact Mass	572.12500
PSA	158.27000
LogP	4.52380

b-D-Ribofuranos...

CAS#:6974-32-9

2-Thiouracil

CAS#:141-90-2

~58%

2’,3’,5’-Tri-O-...

CAS#:21052-18-6

Literature: Vorbrueggen, Helmut; Bennua, Baerbel Chemische Berichte, 1981 , vol. 114, # 4 p. 1279 - 1286

b-D-Ribofuranos...

CAS#:6974-32-9

2’,3’,5’-Tri-O-...

CAS#:21052-18-6

Literature: El-Tayeb, Ali; Qi, Aidong; Nicholas, Robert A.; Mueller, Christa E. Journal of Medicinal Chemistry, 2011 , vol. 54, # 8 p. 2878 - 2890

Precursor 2
CAS#:6974-32-9 b-D-Ribofuranos... CAS#:141-90-2 2-Thiouracil
DownStream 4
CAS#:29123-25-9 2-Thiouridine 5... CAS#:35763-29-2 2-Thiouridine5'... CAS#:20235-78-3 thiouridine CAS#:1748-04-5 Uridine,2',3',5...