Bis-(N,N'-NHS-PEG4)-Cy5

Modify Date: 2024-01-09 21:21:59

Bis-(N,N'-NHS-PEG4)-Cy5 Structure
Bis-(N,N'-NHS-PEG4)-Cy5 structure
Common Name Bis-(N,N'-NHS-PEG4)-Cy5
CAS Number 2107273-48-1 Molecular Weight 1081.64
Density N/A Boiling Point N/A
Molecular Formula C55H73ClN4O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-(N,N'-NHS-PEG4)-Cy5


Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-(N,N'-PEG4-NHS ester)-Cy5

 Bis-(N,N'-NHS-PEG4)-Cy5 Biological Activity

Description Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C55H73ClN4O16
Molecular Weight 1081.64

 Safety Information

Hazard Codes Xi