R18 TFA
Modify Date: 2025-08-26 13:09:07
R18 TFA structure
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Common Name | R18 TFA | ||
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| CAS Number | 211364-78-2 | Molecular Weight | 2309.686 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C101H157N27O29S3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of R18 TFAR18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1[1]. |
| Name | L-Prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-α-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-α-aspartyl-L-leucyl-L-α-glutamyl-L-alanyl-L-asparaginyl-L-methionyl-L-cysteinyl-L-leucyl-L-proline |
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| Synonym | More Synonyms |
| Description | R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C101H157N27O29S3 |
| Molecular Weight | 2309.686 |
| Exact Mass | 2308.080322 |
| LogP | 2.90 |
| Index of Refraction | 1.680 |
| L-Proline, L-prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-α-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-α-aspartyl-L-leucyl-L-α-glutamyl-L-alanyl-L-asparaginyl-L-methio
 nyl-L-cysteinyl-L-leucyl- |
| L-Prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-α-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-α-aspartyl-L-leucyl-L-α-glutamyl-L-alanyl-L-asparaginyl-L-methionyl-L-cyste
 inyl-L-leucyl-L-proline |