6-Amino-5-nitropyridin-2-one

Modify Date: 2024-01-07 08:25:54

6-Amino-5-nitropyridin-2-one Structure
6-Amino-5-nitropyridin-2-one structure
Common Name 6-Amino-5-nitropyridin-2-one
CAS Number 211555-30-5 Molecular Weight 155.11100
Density 1.54g/cm3 Boiling Point 305.9ºC at 760 mmHg
Molecular Formula C5H5N3O3 Melting Point N/A
MSDS N/A Flash Point 138.8ºC

 Use of 6-Amino-5-nitropyridin-2-one


6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine[1].

 Names

Name 6-amino-5-nitro-1H-pyridin-2-one
Synonym More Synonyms

 6-Amino-5-nitropyridin-2-one Biological Activity

Description 6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine[1].
Related Catalog
References

[1]. Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363(6429):884-887.

 Chemical & Physical Properties

Density 1.54g/cm3
Boiling Point 305.9ºC at 760 mmHg
Molecular Formula C5H5N3O3
Molecular Weight 155.11100
Flash Point 138.8ºC
Exact Mass 155.03300
PSA 104.70000
LogP 0.96970
Vapour Pressure 0.000799mmHg at 25°C
Index of Refraction 1.634
Storage condition 2-8℃

 Synthetic Route

~74%

6-Amino-5-nitropyridin-2-one Structure

6-Amino-5-nitro...

CAS#:211555-30-5

Literature: Huttert, Daniel; Benner, Steven A. Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9839 - 9842

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6-Amino-5-nitropyridin-2-one Structure

6-Amino-5-nitro...

CAS#:211555-30-5

Literature: Huttert, Daniel; Benner, Steven A. Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9839 - 9842

 Synonyms

2(1H)-Pyridinone,6-amino-5-nitro
6-AMINO-5-NITROPYRIDIN-2-OL
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Price: ¥770/10 mM * 1 mL in DMSO

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