Mal-(CH2)5-Val-Cit-PAB-Eribulin

Modify Date: 2024-01-13 23:37:32

Mal-(CH2)5-Val-Cit-PAB-Eribulin Structure
Mal-(CH2)5-Val-Cit-PAB-Eribulin structure
Common Name Mal-(CH2)5-Val-Cit-PAB-Eribulin
CAS Number 2130869-21-3 Molecular Weight 1328.54
Density N/A Boiling Point N/A
Molecular Formula C69H97N7O19 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-(CH2)5-Val-Cit-PAB-Eribulin


Mal-(CH2)5-Val-Cit-PAB-Eribulin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-microtubule agent, Eribulin, linked via linker Mal-(CH2)5-Val-Cit-PAB[1].

 Names

Name Mal-(CH2)5-Val-Cit-PAB-Eribulin

 Mal-(CH2)5-Val-Cit-PAB-Eribulin Biological Activity

Description Mal-(CH2)5-Val-Cit-PAB-Eribulin is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-microtubule agent, Eribulin, linked via linker Mal-(CH2)5-Val-Cit-PAB[1].
Related Catalog
In Vitro Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules[2].
References

[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. Patent US20170252458A1.

[2]. Watanabe K, et, al. Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo. Oncotarget. 2019 Jan 4; 10(2): 161-174.

 Chemical & Physical Properties

Molecular Formula C69H97N7O19
Molecular Weight 1328.54
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Price: ¥12500/500 μg

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