CI-39
Modify Date: 2024-01-06 10:13:03
CI-39 structure
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Common Name | CI-39 | ||
|---|---|---|---|---|
| CAS Number | 2132412-25-8 | Molecular Weight | 338.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H18N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CI-39CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 µM and an CC50 of >30 µM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup[1]. |
| Name | CI-39 |
|---|
| Description | CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 µM and an CC50 of >30 µM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup[1]. |
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| Related Catalog | |
| Target |
HIV-1 (WT):3.40 μM (EC50) HIV-1 (WT):>30 μM (CC50) |
| In Vitro | CI-39 (0-100 µM) inhibits HIV-1 RT DNA polymerase and ribonuclease H activities with EC50s of 7.20, >30 µM, respectively[1]. CI-39 shows antiviral activities with EC50s of 3.37, 3.00, 2.41, 3.08, 2.14, 3.27, 3.19, 4.07 µM for VSVG/HIV-1wt, VSVG/HIV-1RT-K103N, VSVG/HIV-1wtRT-K103N, VSVG/HIV-1RT-K1RT-Y181C, VSVG/HIV-1RT-K1RT-K103N,Y181C, VSVG/HIV-1RT-K103N,Y181C, VSVG/HIV-1RT-L100I,K103N, VSVG/HIV-1RT-Y188L, VSVG/HIV-1RT-K103N,G190A, VSVG/HIV-1RT-K103N,V108I, respectively[1]. |
| References |
| Molecular Formula | C19H18N2O4 |
|---|---|
| Molecular Weight | 338.36 |